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NFL teams traveling cross-country often face unique challenges that can impact their performance, such as time zone adjustments, increased fatigue, and disrupted routines. These factors can influence the point spread in betting analysis, as oddsmakers take into account the potential disadvantages for the traveling team. For instance, East Coast teams heading to the West Coast or vice versa might see a shift in the spread to account for the travel burden. Analyzing these dynamics is crucial for bettors, as understanding travel impacts can lead to more informed betting decisions.